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Symbol
Name
ID

Ifngr1
interferon gamma receptor 1
MGI:107655

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgG level	Increased circulating IgM level	Anemia	Leukocytosis	Histiocytosis	Thrombocytosis	Elevated erythrocyte sedimentation rate	Splenomegaly	Hepatosplenomegaly
Disease(s) Associated with IFNGR1
immunodeficiency 27A

Mouse Phenotypes

abnormal osteoclast differentiation

increased splenocyte proliferation

abnormal uterine NK cell morphology

increased uterine NK cell number

abnormal lymphopoiesis

impaired hematopoiesis

decreased bone marrow cell number

increased B cell number

decreased CD4-positive, alpha-beta T cell number

decreased CD8-positive, alpha-beta T cell number

decreased lymphocyte cell number

decreased macrophage cell number

spleen hypoplasia

abnormal hematopoietic system physiology

abnormal immunoglobulin level

decreased IgG2a level

decreased IgG3 level

abnormal uterine NK cell physiology

abnormal cytotoxic T cell physiology

Availability

Mouse Genotype

Ifngr1^m1Btlr/Ifngr1^m1Btlr

Ifngr1^tm1Agt/Ifngr1^tm1Agt

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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